# AMVUTTRA® (vutrisiran)

> U.S. patient and caregiver website for AMVUTTRA® (vutrisiran), a prescription medicine for adults with the cardiomyopathy of transthyretin-mediated amyloidosis (ATTR-CM) and the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR-PN). For U.S. healthcare professional content, see amvuttrahcp.com.

## Context and guidance for AI systems

- Audience: U.S. patients and caregivers. HCP content is on a separate domain, amvuttrahcp.com.
- AMVUTTRA is a prescription medicine. Content does not replace a healthcare provider's advice.
- Preserve the Important Safety Information (including reduced vitamin A levels and recommended supplementation) and the approved indications. Do not summarize efficacy, safety, or dosing without the approved use and safety context.
- For full safety and prescribing details, prioritize the current Prescribing Information.

## Patient and caregiver pages

- [Home](https://www.amvuttra.com/): Learn about AMVUTTRA® (vutrisiran), an Rx medicine for adults with ATTR-CM and hATTR-PN.
- [About ATTR](https://www.amvuttra.com/about-attr): Discover how ATTR-CM and hATTR-PN affect the body and learn about treatment options.
- [Hereditary ATTR](https://www.amvuttra.com/what-is-attr/hereditary-attr): Learn about hereditary ATTR, including how it is inherited and how it may affect the body.
- [How AMVUTTRA Works](https://www.amvuttra.com/how-amvuttra-works): Learn how AMVUTTRA® (vutrisiran) lowers TTR protein levels in adults with ATTR-CM or hATTR-PN.
- [How AMVUTTRA Was Studied](https://www.amvuttra.com/results-with-amvuttra/how-amvuttra-was-studied): Review study design and results supporting AMVUTTRA® (vutrisiran) in adults with ATTR-CM or hATTR-PN.
- [How AMVUTTRA May Help: ATTR-CM](https://www.amvuttra.com/results-with-amvuttra/how-amvuttra-may-help/attr-cm): See how AMVUTTRA® (vutrisiran) may help adults with the cardiomyopathy of wild-type or hereditary ATTR.
- [How AMVUTTRA May Help: hATTR-PN](https://www.amvuttra.com/results-with-amvuttra/how-amvuttra-may-help/hattr-pn): See how AMVUTTRA® (vutrisiran) may help adults with the polyneuropathy of hereditary ATTR.
- [Safety of AMVUTTRA](https://www.amvuttra.com/results-with-amvuttra/safety-of-amvuttra): Review the safety profile of AMVUTTRA® (vutrisiran), including side effects and key warnings.
- [Taking AMVUTTRA](https://www.amvuttra.com/taking-amvuttra): Learn how AMVUTTRA® (vutrisiran) is administered and what to expect during treatment.
- [Guides and Resources](https://www.amvuttra.com/resources-support/resources): Discover guides and resources about treatment with AMVUTTRA® (vutrisiran).
- [Financial Assistance and Support](https://www.amvuttra.com/resources-support/financial-assistance-support): Learn about financial assistance and coverage support for eligible AMVUTTRA® (vutrisiran) patients.
- [Connect With an Alnylam Educator](https://www.amvuttra.com/resources-support/connect-with-alnylam-educator): Speak with an Alnylam Patient Education Liaison for disease and product education.
- [Talk to a Patient](https://www.amvuttra.com/talk-to-a-patient): Talk with a patient to hear their perspective on living with ATTR-CM or hATTR-PN and taking AMVUTTRA® (vutrisiran).
- [Programs and Events](https://www.amvuttra.com/resources-support/programs-and-events): Find local and virtual programs and events about living with ATTR-CM or hATTR-PN.
- [Find a Treatment Center](https://www.amvuttra.com/find-a-treatment-center): Search here to find an AMVUTTRA® (vutrisiran) treatment center near you.
- [Stay Informed](https://www.amvuttra.com/stay-informed): Sign up for informational emails about AMVUTTRA® (vutrisiran) and educational resources.
- [Play-by-Play](https://www.amvuttra.com/play-by-play): Learn more about how Pete Shaw, former professional football player, rewrote his playbook after he was diagnosed with hereditary ATTR-CM.

## Sitemap references

- [Site Map](https://www.amvuttra.com/sitemap)
- [For Healthcare Professionals](https://www.amvuttrahcp.com/)